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News & Announcements

Eskişehir Osmangazi University-ESTEM and AvciBio Research Group took part in the high technology platforms meeting within the scope of TÜBİTAK-1004 Center of Excellence Support Program at TÜBİTAK Gebze Campus, with the participation of Minister of Science, Industry and Technology Mehmet Fatih Kacır, Chairman of the Council of Higher Education (YÖK) Prof. Dr. Erol Özvar and TÜBİTAK President Prof. Dr. Hasan Mandal on August 23rd, 2023.
The projects of 20 consortium platforms have discussed the latest outcomes and related activities with future directions. In this regard, 252 different projects were organized which were established by the cooperation of universities and industrial research centers/infrastructures. Over 70 universities, 109 private sector institutions, 6 research infrastructures, 6 public R&D units and 1550 researchers were involved in this event.
It is aimed that the platforms framework will increase the competitiveness of our country and interconnect the works that create an added value in Turkiye's development journey. It has also been pinpointed that these platforms contribute to the goal of raising the quality of the human resources required for the development of our national technology.
On April 22, 2022, Deans of the Faculty of Medicine; the Faculty of Engineering and Architecture; and the Faculty of Science and Letters Prof.Dr. Özkan ALATAŞ, Prof.Dr. Muammer KAYA and Prof. Dr. Emin UĞURLU visited the Cell Therapy and Stem Cell Production, Application and Research Center (ESTEM) and AvciBio Research Group. The meeting covered information, publicity and promotional activity of our facilities and current projects.
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Department of Otolaryngologist at Eskisehir Osmangazi University visited our lab and then we discussed possible new projects to further enhance our collaboration on April 6, 2022.
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Congratulations! We are proud to announce that Dr. Ceren Özel, a scientist at Eskişehir Osmangazi University-ESTEM and AvciBio Research Group, has been awarded the third prize in the "2023 Best Paper Award" international competition, organized by Sabancı University - Functional Surfaces and Interfaces Center of Excellence for Nano Diagnosis (EFSUN) on August 21st, 2023. We wish our esteemed researcher, Dr. Özel, continued success in her career.
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We were proud to having two workshops in a day on March 1, 2022. The workshop was hosted by Eskişehir Osmangazi University with partnership of Cellular Therapy and Stem Cell Production, Application and Research Center (ESTEM), Translational Medicine Research and Clinical Center (TATUM), and Avcibio Research Group. Distinguised Professors Ali Koşar, Levent Trabzon, Barbaros Cetin, Ender Yıldırım, Huseyin Cumhur Tekin, who have conducting pioneering research and work in the field as speakers. Participation for the workshop was limited due to the pandemic.




 
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TÜBİTAK 1004 Center of Excellence Support Program Experience Sharing and Promotion Ceremony was held on 30 April 2023 as part of Teknofest-Istanbul 2023 with the participation of Ministry of Science, Industry and Technology Mustafa VARANK and TÜBİTAK President Prof. Dr. Hasan MANDAL. The high-tech platforms, including ESOGU-ESTEM, carried out within this scope, presented their experiences by combining industry, university and public partners, and at the same time, the signing ceremony of the new high-tech platforms was held with the participation of the rectors of the universities.
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Congratulations! We are so proud that Dr. Ceren Özel, MSc and PhD, received her PhD from department of Stem Cell, ESTEM, a member of AvciBio Research Group for being awarded the 2022 Eskişehir Osmangazi Üniversitesi Health Sciences Institute Best Dissertation Award. ESOGÜ Awards are given every year in order to evaluate the success and performance of our university faculty members and students in their academic studies, to encourage and support them.
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We had extreme pleasure of hosting a national news agency for a video report in Eskişehir Osmangazi University Cellular Therapy and Stem Cell Production Application and Research Center (ESTEM) and AvciBio Research Group on March 17, 2023.
They emphasized our varieties of works bringing together different disciplines, R&D programs and some of the world's most innovative research environments. The news agency showed how original solutions can be developed for our country to go one step further with its research capacity and research infrastructure. It was emphasized that with organ on a chip technology in which a personalized medicine can be developed in a short time with a relatively low cost, high efficiency and safety as well as acceleration the development of new drugs and their rapid entry into the market.
For detailed information click here for press news and click here  for videos (in Turkish).
For detailed information click here for press news and click here  for videos about ESTEM (in Turkish).
On April 8th 2023, it was our pleasure and honor to host the President of TÜBİTAK, Prof. Dr. Hasan Mandal at Eskişehir Osmangazi Üniversitesi ESTEM and AvciBio Research Group. During this notable visit, we demonstrated our state-of-the-art studies on stem cells & isolation, characterization, cellular therapy, microfabrication, microfluidics, tissue engineering, organ-on-a-chip, biosensors, biomaterials and 3D bioprinting with our mission conducting by our multi and interdisciplinary group from engineering to medicine, fundamental science to pharmaceutical.

We really appreciate TÜBİTAK supporting for our scientific research with all level of students, postdocs and visiting scholars.

We are expressing our many thanks to Prof. Dr. Hasan Mandal for his kind visit, valuable advice and support which are very important and encouraging.
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Congratulations! Our project about microfluidic chip based microfiltration platform for selectively removal of biological target molecules has been awarded funding from TUBITAK 3501 Career Development Program.
We got the acceptance of our project entitled "Development of an Optical Based pH Sensor for Continuous and High Sensitivity pH Measurement in Different Cell Media Environments" by The Scientific and Technological Research Council of Türkiye (TÜBİTAK) under the category of TÜBİTAK 1005-National New Ideas and New Products Research Funding Program.
Congratulations to the team!
Three projects by our group members have been found worthy to be supported by TÜBİTAK 2218-National Postdoctoral Research Fellowship Programme for the next two years:

•  Evaluation of primary hepatocytes in liver on a chip system which is proposed by Dr. Murat KAYA under the supervision of Assoc. Prof. Hüseyin Avci and Assist. Prof. Onur Uysal at ESOGU-ESTEM. 
•  Investigation of combinations of nanoparticles with exosome and anti-cancer agents in stem cells using microfluidic system that is proposed by Dr. Bahar DEMİR CEVİZLİDERE under the supervision of Assoc. Prof. Gülay Büyükköroğlu at Anadolu University. 
•  A regeneration approach of mesenchymal stem cells for hepatotoxicity by using organ on a chip platform which is proposed by Dr. Özlem TOMSUK under the supervision of Assoc. Prof. Ender Yıldırım at Middle East Technical University. 
Congrats Roshan Javanifar for passing his doctoral qualification exam on January 12th, 2023! He will work on microfluidic chips integrated micro-filtration systems.
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Congratulations! Our undergraduate students Hasret Sena Eşkin, Yiğithan Bulut and Onur Gündoğdu have successfully completed their undergraduate projects. In their undergraduate thesis, they worked on investigation of cell culture in microfluidic systems. We wish our dear students success in their life journey.
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On January 20, 2022,  Eskisehir Osmangazi University Rector Prof. Dr.Dr.jur.h.c. Kemal Şenocak, LL.M, Vice Rectors of Prof. Dr. Ali Arslantaş and Prof. Dr. Rifat Edizkan visited Cellular Therapy and Stem Cell Production, Application and Research Center (ESTEM), and AvciBio Research Group's Micro Electro-Mechanical System (MEMS) and Tissue Engineering Research Laboratories. Director of ESOGÜ-MEMS and Tissue Engineering Research Labs Assoc. Prof. Dr. Huseyin Avci, and colleagues Assoc. Prof. Dr. Ayla Eker Sariboyaci, Assoc. Prof. Dr. Eray Atalay and Assist. Prof. Dr. Onur Uysal provided information about the current studies carried out in the center.
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Dr. Huseyin Avci has received Eskisehir Osmangazi University 2021 Scientific Research Project Incentive Award
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A Lean lab training was conducted by Assistant Professor Nurcan DENİZ, from Eskişehir Osmangazi University (ESOGU) Faculty of Economics and Administrative Sciences for our team for improving efficiencies and effectiveness on Wednesday, December 01, 2021 at Cellular Therapy and Stem Cell Production, Application and Research Center (ESTEM) with the participation of ESTEM and AvciBio research groups.






 
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Good Manufacturing Practices (GMP) Compliance Training was held on Tuesday, November 16, 2021 at Cellular Therapy and Stem Cell Production, Application and Research Center (ESTEM) with the participation of ESTEM and AvciBio research groups, by the Turkey Pharmaceuticals and Medical Devices Agency.







 
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Avcibio team is a Finalist in Teknofest Technology for Humanity competition in the Health and First Aid category. The final stage of the competition will be held 21 - 26 September 2021 at İstanbul Atatürk Airport.
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A research project titled “On chip co-culture of liver cells under interstitial flow” proposed by Dr. Ahmet Emin TOPAL under the supervision of Assoc. Prof. Hüseyin Avci and Assoc. Prof. Ayla Eker Sariboyaci has been found worthy to be supported by TÜBİTAK 2218-National Postdoctoral Research Fellowship Programme 2021/1. Dr. Topal will carry out his research work as a Visiting Scholar at the ESTEM-MEMS and Tissue Engineering Lab (AvciBio Research Group) at Eskisehir Osmangazi University for the next two years.
Congratulations to the team! 
Leading by Ankara University Stem Cell Institute, our project has been awarded grant funding under TUBITAK 1004-Regenerative and Restorative Medicine Research and Applications with the aim of developing a 3-dimensional liver chip kit for clinical diagnosis (2021). 
Asst. Prof. Seyed Ali Mousavi Shaegh's presentation titled "How to do multidisciplinary clinical research? Insights from medical device design in orthopedic surgery" will be held on 23th of January, 2020 at 10:30 a.m. in ESOGU Teaching Hospital Meeting Room.









 
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Our collaborative work with Dr. Fatma Dogan Guzel's research group at Ankara Yildirim Beyazit University and Dr. Hossein Hashempour's group at Azarbaijan Shahid Madani University titled as "Development of a cost effective and highly sensitive on-chip platform: Cyclotides on a Chip" is granted by bilateral TUBITAK and Iran Centre for International Scientific Cooperation of the Ministry of Science, Research and Technology (2020). 
Congratulations to the team!
Yücel successfully defended his master's thesis on December 15th, 2021 with a title of "Investigation of Biosensor Development by Using Electrochemical Impedance Spectroscopy".
Congratulations Yücel, for successfully completing your MSc in Chemical Engineering!
Congrats to Yucel of his first paper and co-authors for the publication on electrochemical biosensor: 
https://onlinelibrary.wiley.com/doi/abs/10.1002/elan.202060433
Congratulations to our team! Our recent paper about SEBS nanofibers for bioengineering and water filtration applications has been published as a cover on Journal of Applied Polymer Science (2020)!

 
Our collaborative work with Harvard Medical School, University of Connecticut, University of Nebraska and University of Victoria about engineering skeletal muscle tissue by using a textile technique is highlighted on ACS Biomaterials Science & Engineering (2020) journal's cover!
Our project about evaluation of controlled drug release in mesenchymal stem cell-loaded composite living-fibers of biotextile (2020) is granted by TUBITAK-1002 - Short Term R&D Funding Program! Congrats Ceren Ozel!
Congrats Ceren Ozel and Bahar Demir Cevizlidere for passing prelim!  November 27th, 2019






 
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The Dean of the Faculty of Medicine; Prof. Dr. Özcan ÖZDEMİR and the Vice Dean Prof. Dr. Engin ÖZAKIN visited ESTEM and AvciBio Research Group on December 28th, 2022. During the visit, we shared information about our research activities and current projects with the pleasant conversation, especially on possible issues within the scope of bilateral cooperation.
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On December 19th, 2022,  Eskisehir Osmangazi University Rector Prof. Dr. Kamil Çolak, Vice Rectors of Prof. Dr. Kürşat Bora Çarman, Prof. Dr. Ramazan Erdağ, and Prof. Dr. Hakan Demiral visited Cellular Therapy and Stem Cell Production, Application and Research Center (ESTEM), and AvciBio Research Group's Micro Electro-Mechanical System (MEMS) and Tissue Engineering Research Laboratories. ESTEM manager Assoc. Prof. Dr. Ayla Eker Sariboyaci and director of ESOGÜ-MEMS and Tissue Engineering Research Labs Assoc. Prof. Dr. Huseyin Avci with colleagues Assoc. Prof. Dr. Eray Atalay and Assist. Prof. Dr. Onur Uysal provided information about the current studies carried out in the center.
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Congratulations Ceren Ozel on achieving her PhD degree, November 2th, 2022. It is undoubtedly a big stepping stone towards for her brighter future. Dr. Ozel’s dissertation has a great contribution with insights to the both microphysiologic liver on a chip system and biomimetic approaches for engineering biotextile for treatment of skin injuries. Great papers are on the way; stay tuned!
ESTEM and AvciBio Research Group participated in Eskişehir Industry Fair 2022, the 2nd R&D Industry and Technology Fair held at Eskişehir Chamber of Commerce- TÜYAP Fair Center on October 18-21, 2022, to present innovative health related products from our laboratories.

During COVID-19 pandemic as all of us faced changing and expanding scope of the defense industry in Turkiye and in the world, like this pandemic is not just as a health problem; at the same time, the similar pandemic or chemical and biological threats probably we will face in the future at some degree. These threats as global problems in the axis of society, security, economy, culture and politics, places the issue of biosecurity in the focus of the defense sector, while at the same time expanding the scope of the defense industry with new security parameters. In this sense, the importance of innovative products in the field of health is becoming more and more important.
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Congratulations to Ceren Ozel for receiving the  TUBITAK Scholarship 2019!
Our project about new generation fibers (2018) was granted by TUBITAK-1003 Primary Subjects R&D Funding Program!
Congrats to Ceren and her co-authors and first paper for the publication on: Organ-on-a-Chip:  https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202100333R
We are excited to share that our research paper was published in Biotechnology and Applied Biochemistry is among the top 10 most downloaded papers!!!

Congrats to the team and special thanks to Fatma Doğan Güzel and AvciBio Research Group.
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Congratulations to the undergraduate students for their successful thesis defense on January 26th, 2022. Special thanks to Asst. Prof. Dr. Mine TOKER and Asst. Prof. Dr. Hamed GHORBANPOOR as committees, and AvciBio Research Group members. 
Congratulations to undergraduate students for successfully completing their BSc in Metallurgical and Materials Engineering!
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On 11-12 May 2022, AvciBio Research Group members participated in the R&D Projects Dissemination Event in Turkey held at Adıyaman University and Kütahya Dumlupınar University to present some current innovative projects in the lab. Governor of Adiyaman and Rector of Adiyaman University have visited our stand with a great interest.
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June 10th, 2022, Tayfun Şengel successfully passed the doctoral qualification exam. 
In addition, our undergraduate student Ulku Sonmez has successfully completed her graduation project on microfluidic production and characterization from thermoplastic-based polymers.
Congratulations!
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We were proud to host Dr. Shabir Hassan as distinguished scientist, Early-Stage investigator at Harvard University, on August 5, 2022, at 14:30 Eskişehir Osmangazi Üniversitesi Prof. Dr. Necla Özdemir Hall. The seminar was organized by Eskisehir Osmangazi University with partnership of Cellular Therapy and Stem and Stem Cell Production, Application and Research Center (ESTEM), Translational Medicine Research and Clinical Center (TATUM) and AvciBio Research Group. 

Dr. Hassan presented a great talk titled as “Whirlpool in a cup, organs in your pocket: Recent advances in Bioengineering Insights from medical device design in orthopedic surgery". Thanks to all participants from engineering to medicine, fundamental science to dentistry and even to department of education and economics with administrative sciences!


 
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Microengineering Cell Based Lab-on-a-Chip Devices: Advancing Organ-on-a-Chip Technology
 



Cell Death Research Society 




June 16, 2023
 

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